OEIS Complex
A combination of defects comprising OMPHALOCELE, exstrophy of the cloaca, ANUS IMPERFORATE, and spinal defects. This rare complex is thought to represent the most severe end of a spectrum of birth defects, the exstrophy-epispadias sequence, which, in order of increasing severity, includes phallic separation with EPISPADIAS, pubic diastasis, EXSTROPHY OF THE BLADDER, and CLOACAL EXSTROPHY. (From OMIM 258040)